South West Anaesthesia Research Matrix



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This is a multi-centre, open-label, pragmatic, individually randomised, parallel group, superiority trial and economic evaluation to determine the clinical and cost effectiveness of SGA versus TI during IHCA. The trial will be conducted in the acute setting in NHS hospitals throughout the UK.

An internal pilot study will confirm the feasibility of the trial. An integrated economic evaluation will assess the cost-effectiveness of SGA compared with TI.

The primary outcome is the Modified Rankin Scale (mRS) score assessed at hospital discharge or 30 days following IHCA, whichever occurs sooner.